Oral Pills Oral Pills Most second-line ITP therapies are available as oral pills, including the TPO-RAs eltrombopag (Promacta) and avatrombopag (Doptelet), the SYK inhibitor fostamatinib (Tavalisse), the BTK inhibitor rilzabrutinib (Wayrilz), and MMF (CellCept). The TPO-RAs are taken once a day and the other drugs are taken twice a day.e60dc2a1-f33c-4a05-9b50-8e3e8e597629bba8ac75-1d41-40a3-9836-551f8b3e3b41 Medical Monitoring Requirements Of the two oral TPO-RAs, “avatrombopag does not have hepatotoxicity that can be seen with eltrombopag,” says Cindy Neunert, MD , a hematologist at Columbia University Irving Medical Center in New York City…
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