Autoimmune problems can affect both children and adults with PI. They’re especially common in certain types of PI, including common variable immune deficiency, complement deficiencies, Good syndrome, hyper immunoglobulin M syndrome, idiopathic T cell lymphocytopenia, selective immunoglobulin A deficiency, and Wiskott-Aldrich syndrome.
While there’s no proven way to prevent autoimmune diseases in people with PI, staying proactive about your healthcare may make a difference. “We can’t really predict which patients will develop autoimmune disease,” says Ballow. “However, if we do genetic testing and we define a genetic abnormality … we can follow you a little more closely and perhaps catch an autoimmune process a little earlier.”
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