Is Berberine Really Nature’s Ozempic?
Berberine is a supplement derived from shrubs such as barberry, Oregon grape, and tree turmeric. It usually comes in capsule or powder form.
To understand berberine’s attraction, look no further than its price tag: A monthlong supply retails for $20 to $40.
But the effects of berberine have been examined only in small, short-term studies, Dr. Parker says, and “average weight loss is approximately 2 to 3 percent of body weight.” That percentage isn’t insignificant, but it doesn’t compare with semaglutide, which can help people lose as much as 15 percent of their body weight.
Plus the evidence of berberine’s benefits is limited. The available evidence isn’t enough to support most health claims about berberine, Dr. McGowan says.
Still, berberine is a relatively low-risk supplement to try. “In my opinion, berberine is generally safe and well tolerated, with GI side effects being the most common complaint,” Parker says.
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