Side Effects of Retinaldehyde
The main side effects of topical retinoids like retinaldehyde are redness, dryness, scaly skin, and irritation. These effects can happen with any topical retinoid, and they tend to be more severe as the dose and concentration increase.
Companies often market retinaldehyde as a less-irritating form of retinol than retinoic acid, says Fine. But it’s likely not as effective at decreasing the signs of wrinkles and pigmentation as the prescription topical, she says. Fortunately, there are ways to buffer side effects (more on this below).
Don’t use topical retinoids, including retinol or retinaldehyde, if you are pregnant, says Friedler. “Systemic absorption of these products is probably low, but we always want to be abundantly cautious,” she adds. Benzoyl peroxide, azelaic acid, salicylic acid, and glycolic acid are considered safe for use during pregnancy, but check with your healthcare provider to be sure.
Make sure skin conditions like rosacea, eczema, or psoriasis are well controlled before you introduce retinol products, including retinaldehyde, Fine says. “If you begin from a place where your skin barrier is compromised, it will only become more irritated.” If your skin is in a good place, start the application slowly and consult your dermatologist.
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