Ulcerative Colitis and Anemia: What’s the Link?

Staff
By Staff
4 Min Read

The best treatment for anemia with UC depends on the cause. In general, managing UC-related anemia involves both medical management and lifestyle adjustments.

Medical Treatments

The best way to treat UC-related anemia is to manage ulcerative colitis. This can help control the bleeding in the large intestine to limit blood loss (and the resulting iron deficiency anemia) and reduce inflammation to treat ACD.

Medicines to treat UC include:

  • Aminosalicylates
  • Corticosteroids
  • Immunosuppressants
  • Biologics
  • Small-molecule medicines
People with severe bleeding or disease that doesn’t respond to medications may need surgery that removes part of the rectum and colon and alters the way the body processes stool, like an ileostomy or ileoanal reservoir surgery.
If the cause of anemia is iron deficiency, treatment will involve iron supplementation in the form of an oral supplement. Those who have an active UC flare or don’t tolerate oral supplements well may receive iron intravenously; iron delivered via an IV is more easily absorbed and can raise your iron stores quicker. A healthcare provider may also prescribe vitamin B12 and folic acid supplements if necessary.
Blood transfusions, or the replacement of a specific volume of blood with healthy donated red blood cells, may be necessary for people with severe ACD or in those with severe rectal bleeding.

Bhargava says the key to treating his iron deficiency was getting his ulcerative colitis under control so his body could absorb iron properly.

Although the hospital treatment helped his ulcerative colitis symptoms, Bhargava continued to be deficient in iron. “It was challenging just to get up in the morning and go to work,” he says. “And because the tiredness was getting worse, the frequency of bowel movements would get worse, and I’d lose more blood with every bowel movement.”

After speaking with an hematologist at the hospital in New York City where he worked, Bhargava tried intravenous iron infusions and vitamin B12 injections, treatments commonly used to counteract chemotherapy side effects.

“It almost instantaneously helped my energy levels,” he says. “And it also helped my colitis symptoms.”

If your symptoms improve and your UC stays in remission, you’ll likely be tested for anemia every 6 to 12 months. Those with active disease and symptoms should undergo screening every three months. People living with UC should also receive annual screening for vitamin B12 and folic acid, as low levels of these can also cause anemia.

Lifestyle Factors

In addition to medical treatments, dietary modifications can help manage UC flare-ups. These include:
  • Identifying and avoiding trigger foods, like dairy or high-fiber foods
  • Drinking fluids often
  • Limiting or avoiding drinks containing alcohol and caffeine

Physical exercise and managing stress can also prevent flares and preventing flares may help decrease likelihood of developing iron deficiency.

Bhargava became a vegetarian and started practicing pranayama, a form of yoga breathing. He also takes ayurvedic herbal supplements and remains free of both UC and iron deficiency symptoms.

After your body’s iron stores are back up, eating iron-rich foods such as the following can help maintain them:

  • Iron-fortified cereals
  • Oysters
  • Beans
  • Beef
  • Beef liver
  • Spinach
  • Tofu
  • Sardines
  • Canned or stewed tomatoes

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