Why Is the Human Metapneumovirus (HMPV) Spiking in China?

Staff
By Staff
6 Min Read
A sharp increase in respiratory viral infections in China — especially from human metapneumovirus (HMPV) — has public health officials in the United States on the alert.

This spike in HMPV-related illness, however, is not unusual for this time of year, and authorities are urging people not to worry that this is the first sign of a potential pandemic.

“The CDC is in regular contact with international partners and monitoring reports of increased disease,” says Belsie González, MPH, a spokesperson for the Centers for Disease Control and Prevention. “Recent reports of increased HMPV activity in China are not currently a cause for concern in the U.S., though some transmission of HMPV can be expected throughout the year in the U.S., especially during the winter respiratory virus season.”

While some people with HMPV need to be hospitalized for bronchitis or pneumonia, most experience mild upper respiratory symptoms similar to the common cold and recover after a few days.

What Is HMPV and Why Isn’t It More Well Known?

In the same family of viruses as RSV (respiratory syncytial virus), HMPV is a common respiratory virus that is most active in winter through to spring.
Although first detected in 2001, HMPV may have been circulating since at least the 1950s, according to tests of archived blood samples.
Despite being widespread in many countries, the virus doesn’t get the same level of attention as RSV, COVID-19, or the flu because its symptoms are often mild and difficult to distinguish from a common cold.

“You don’t hear about HMPV as much because we don’t often test for it, because it doesn’t send a lot of people to the hospital,” says Panagis Galiatsatos, MD, a pulmonary and critical care physician with Johns Hopkins Medicine in Baltimore and a volunteer medical spokesperson for the American Lung Association. “We will screen for viruses that are very common to send you to the hospital. The only times I even request a screening for HMPV are in my ICU patients who are immunosuppressed, and I have to figure out what is causing lingering respiratory problems.”

Even with a relatively low level of testing for HMPV, the CDC notes that only 1.4 percent of recent diagnostic tests have been coming back positive.

HMPV Is Like a Bad Cold, With Cough as Top Symptom

“HMPV feels like a cold to most people,” says Peter Chin-Hong, MD, an infectious disease specialist and a professor of medicine at the University of California San Francisco School of Medicine. “It resembles RSV most closely clinically, and predominantly causes only respiratory symptoms.”

Symptoms commonly associated with HMPV include:
  • Cough
  • Fever
  • Congestion
  • Shortness of breath

“The big one is cough,” says Dr. Galiatsatos. “I’ve never met a patient where it wasn’t the leading symptom.”

When HMPV progresses to a more severe infection, wheezing becomes a prominent symptom, indicating inflammation and narrowing of the airways.
Anyone can get HMPV, but the people most at risk of complications are newborns, children under 5, seniors age 65 and older, individuals with asthma who take steroids, COPD patients, and the immunocompromised, such as those who take cancer medications or have had organ transplants.

How to Treat HMPV

Unlike the flu or COVID-19, there is no vaccine or specific antiviral treatment for HMPV.

Most people will recover on their own after a few days with basic supportive care. Here’s how to relieve symptoms:
  • Take pain or fever medications
  • Use a room humidifier or take a hot shower to ease a sore throat and cough.
  • Drink plenty of liquids to stay hydrated.
  • Stay home and rest.

Preventing Spread and Protecting Yourself

HMPV is a highly contagious virus that spreads through respiratory droplets, close contact, or contaminated surfaces.

As with other respiratory viruses, the CDC advises taking the following precautions to help stop the transmission of illness:

  • Avoid close contact with sick people.
  • Wash your hands for at least 20 seconds.
  • Avoid touching your face (especially mouth, nose, and eyes).
  • Cover your mouth and nose when coughing or sneezing.
  • Disinfect objects and surfaces regularly (such as doorknobs, countertops, and light switches).
  • Consider wearing a mask in crowded or poorly ventilated spaces.

Stay Calm and Carry On

China’s reported levels of acute respiratory infections, including HMPV, are within the expected range for the winter season, with no unusual outbreak patterns reported.

With this in mind, Dr. Chin-Hong is urging people to take precautions against respiratory illness, but not to be overly concerned about HMPV becoming a pandemic situation like COVID-19.

“HMPV cases in the U.S. have had a predictable increase since November, but the numbers of cases pale in comparison to the ‘big three’ of influenza, RSV, and COVID,” he says. “The situation is not as worrisome as with COVID because our immune cells are experienced with this pathogen, most cases are mild, and our scientific knowledge base about HMPV is much more robust than when COVID first emerged.”

Read the full article here

Share This Article
Leave a comment

Leave a Reply

Your email address will not be published. Required fields are marked *