Is the Ozempic Pill as Effective as the Ozempic Injection?
Like the Ozempic injection, oral Ozempic can be an effective type 2 diabetes treatment, but it’s important to note that the formulations are absorbed differently by the body and therefore available in different doses.
The Ozempic pill is available in 1.5, 4, and 9 milligram (mg) daily doses, whereas Ozempic injections are available in 0.25, 0.5, 1, and 2 mg weekly doses. The Ozempic pill uses higher amounts of semaglutide than injectable Ozempic, because only a fraction of the semaglutide that enters the stomach is properly absorbed.
A study of real-world data found oral semaglutide demonstrated “similar effectiveness” to injectable semaglutide for blood sugar control. While these results suggest that the Ozempic pill and injectable Ozempic could be similarly effective for people with type 2 diabetes, the two drugs are not equivalent, practically speaking.
When tested in people with type 2 diabetes using metformin, the maximum dose of injectable Ozempic (2 mg) led to an A1C drop of 2.2 percentage points and weight loss of just over 15 pounds. The Ozempic pill is unlikely to match these results — at least not at the approved doses.
Due to the differences in the drugs’ respective dosages and how they’re absorbed by the body, medical supervision is recommended when switching from one form of Ozempic to the other.
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