ATTR-CM and Alcohol: Is Drinking Safe?

Staff
By Staff
3 Min Read

How Alcohol Affects ATTR-CM

ATTR-CM makes the walls of your heart thick and stiff, and reduces its ability to pump enough blood through your body. 

Alcohol directly damages heart muscle cells, which can make ongoing amyloidosis worse, says Dr. Carmona Rubio. Amyloidosis is a general term for abnormal protein buildup in your organs; in the case of ATTR-CM, it involves TTR, which affects your heart. Worsening protein buildup can exacerbate some ATTR-CM symptoms, such as shortness of breath and swelling in your legs.

“For patients with ATTR-CM, drinking alcohol is discouraged,” says Paciulli. “Even in small amounts, it can place extra stress on an already compromised heart.”

It Affects Your Blood Pressure

Alcohol temporarily lowers blood pressure, and ATTR-CM damages the nerves that adjust for blood pressure changes. So when you drink, your heart can’t adjust, and sudden low blood pressure can cause dizziness and fainting, says Carmona Rubio.

It Boosts Your Risk of Arrhythmia

Alcohol can irritate the heart’s electrical system, increasing the risk of dangerous heart rhythms, says Cynthia A. Kos, DO, a cardiologist at the Advanced Heart Failure Center at Hackensack Meridian Jersey Shore University Medical Center in Neptune, New Jersey. “For a heart that is already stiff and struggling to pump, a sudden, fast, or irregular heartbeat can be too much to handle.” This can lead to life-threatening heart problems.
Arrhythmias like atrial fibrillation can make you feel tired, dizzy, breathless, and like your heart is pounding or fluttering. When you have ATTR-CM, people with atrial fibrillation have a very high risk of developing blood clots, says Carmona Rubio.

It Causes Fluid Retention

Drinking alcohol tells your body to hold on to water. When you have ATTR-CM, you have a more fragile fluid balance, and extra water can cause swelling in your legs and fluid in your lungs. More fluid in your lungs can make it hard to breathe, and leg swelling can lower your mobility.

It Dehydrates You

While drinking alcohol with ATTR-CM can lead to too much fluid in your body, you can also easily get dehydrated with this condition, says Paciulli. Because it’s hard for your body to maintain a balanced fluid level with ATTR-CM, medications may remove too much fluid too fast. Alcohol also dehydrates you, which adds to this risk.

“When you’re dehydrated, your blood pressure can drop,” says Dr. Kos. “For a heart that is already weak, trying to pump blood when there isn’t enough fluid and the blood pressure is too low is a huge strain.”

Dehydration with ATTR-CM can also make you feel weak and dizzy, increasing your risk for falls, says Paciulli.

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