Newer GLP-1 weight loss drugs like semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and orforglipron (Foundayo) work by dramatically decreasing your appetite and delaying stomach emptying. Most users find themselves eating less food and losing weight — which makes it even more important to consider the nutritional impact of every bite you take.
Bonnie Newlin, RD, who is based in Annapolis, Maryland, says emphasizing foods rich in specific nutrients is the best approach. “While using a GLP-1 or GIP agonist, I recommend prioritizing protein and fiber,” she says. “Protein plays a crucial role in maintaining muscle mass, while fiber provides essential nutrients and promotes gut health.”
On the flip side, certain foods aren’t great choices for these drugs. Some foods can be harder to digest, increasing the risk of nausea and diarrhea, Newlin says, or could even impede weight loss.
In extreme cases, lack of hunger and unhealthy food choices can even lead to nutritional deficiencies and malnutrition. Here’s what deserves prime real estate on your plate when you’re on a prescription weight loss drug — and which foods to keep to a minimum.
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